产品货号：
Z13740
中文名称：
CEBPB抗体
英文名称：
Anti-CEBPB Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CEBPB Antibody |
| 指标别名 | C/EBP beta;CEBPB;CRP2;IL6DBP;LAP;Liver activator protein;NF IL6;Nuclear factor NF IL6;TCF 5;TCF5;Transcription factor 5 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rabbit,rat |
| 应用范围 | WB,IHC |
| 基因名称 | CEBPB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CEBP Beta recombinant protein (Position:M1-A200).Human CEBP Beta shares 61% amino acid (aa) sequence identity with both mouse and rat CEBP Beta. |
| 实际分子量 | 42KD/46KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CCAAT/enhancer-binding protein beta,also known as is CEBP-beta,is a protein that in humans is encoded by the CEBPB gene.It mapped to 20q13.13.The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions.It can also form heterodimers with the related proteins CEBP-alpha,CEBP-delta,and CEBP-gamma.The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene,as well as to regulatory regions of several acute-phase and cytokine genes.In addition,the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.CEBP-beta is critical for normal macrophage functioning,an important immune cell sub-type.Observational work has shown that expression of CEBP-beta in blood leukocytes is positively associated with muscle strength in humans,emphasizing the importance of the immune system,and particularly macrophages,in the maintenance of muscle function. |
| Uniprot ID | P17676 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | CCAAT/enhancer binding protein (C/EBP),beta |
| 蛋白名全称 | CCAAT/enhancer-binding protein beta |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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